Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomas
نویسندگان
چکیده
منابع مشابه
Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomas
BACKGROUND Wnt inhibitory factor-1(WIF-1) acts as a Wnt-antagonists and tumor suppressor, but hypermethylation of WIF-1 gene promoter and low expression activate Wnt signaling aberrantly and induce the development of various human tumors. With this work we intended to investigate the expression and promoter methylation status of WIF-1 gene in human astrocytomas. METHODS The tissue samples con...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2010
ISSN: 1756-9966
DOI: 10.1186/1756-9966-29-26